AZD-9291
AZD-9291
- CAS:
- 1421373-65-0
- MF:
- C28H33N7O2
- MW:
- 499.61
Suppliers by country/region
Company Type
Properties
- Melting point:
- >188oC (dec.)
- Density
- 1.19±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- pka
- 12.68±0.70(Predicted)
- form
- Solid
- color
- Pale Yellow to Beige
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
- HS Code
- 29339900
Use
AZD-9291 (Mesylate), also known as Osimertinib, belongs to a third-generation EGFR (epidermal growth factor receptor) inhibitor. It can be used for the treatment of locally advanced or metastatic non-small cell lung cancer (NSCLC) in case when the cancer cells carry specific mutations (such as T790M) in the epidermal growth factor receptor. It takes effect through directly binding to the certain mutant forms of EGFR (T790M, L858R, and exon 19 deletions) that are frequently found in NSCLC, further causing poor prognosis for late-stage disease. Since it spares wild type EGFR during therapy, it has only limited toxicity.
3 India supplier list of "AZD-9291"
- Product Name:Mereletinib
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Osimertinib Base
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA
- Product Name:AZD-9291 95% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.094182
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Osimertinib
- Products Intro:Brand:clearsynth | Product Number:CS-O-11962
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Osimertinib
- Products Intro:Brand:pharmaffiliates | Product Number:PA1551000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Osimertinib
- Products Intro:Brand:ajchemicals | Product Number:JDH-35264 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Osimertinib (AZD9291)
- Products Intro:Purity: 98% HPLC | Package: 1g
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Inosine pranobex,Probenecid,Sodium Ceftiofur,3-O-Ethyl-L-ascorbic acid,benzhexol hydrochloride
$0.00/ 1g
- Product Name:Osimertinib
- Products Intro:Purity: 99.9% HPLC | Package: 1kg;|5kg;|10kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Racecadotril,Febuxostat,Ezetimibe,Carboplatin,Cisplatin
$0.00-0.00 / 1kg
- Product Name: AZD-9291
- Products Intro:Purity: 98% | Package: 1KG;5USD|1000KG;0.1USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chemical raw materials,Organic raw materials,Petrochemicals,Chemical reagents,Intermediates
$5.00-0.10 / 1KG