OSI-420
OSI-420
- CAS:
- 183321-86-0
- MF:
- C21H21N3O4
- MW:
- 379.41
Suppliers by country/region
Company Type
Properties
- Melting point:
- 140-142°C
- Density
- 1.30
- storage temp.
- -20°C Freezer
- solubility
- insoluble in H2O; insoluble in EtOH; ≥51 mg/mL in DMSO
- form
- A crystalline solid
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Use
OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.
1 India supplier list of "OSI-420"
- Product Name:Erlotinib6-O-DesmethylMetabolite
- Products Intro:Brand:synzeal | Product Number:183311109
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:OSI-420
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Erlotinib6-O-DesmethylMetabolite
- Products Intro:Brand:pharmaffiliates | Product Number:PA050141022
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:O-DesmethylErlotinib
- Products Intro:Brand:clearsynth | Product Number:CS-O-11869
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Desmethyl Erlotinib
- Products Intro:Purity: > 95% | Package: 5mg | CustNote: BOC Sciences also provides custom synthesis services for Desmethyl Erlotinib.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:OSI-420
- Products Intro:Purity: 98% grace@coreychem.com | Package: 1KG;3.07USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Methyl 3-amino-2-fluorobenzoate
- Product Name:Desmethyl Erlotinib；O-Desmethyl Erlotinib;OSI-420;CP-473420
- Products Intro:Package: 10 mg；5 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:OSI-420
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A812766
- Company Type: Reagent
- Country/Region: CHINA
-
10 mg$303.00
- Product Name:DesmethylErlotinib
- Products Intro:Brand：Caymanchem | Product Number：23394 | Purity：≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:OSI420
- Products Intro:Brand：dcchemicals | Product Number：DC9230 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES