Clotrimazole
Clotrimazole
- CAS:
- 23593-75-1
- MF:
- C22H17ClN2
- MW:
- 344.84
Suppliers by country/region
- India(122)
- CHINA(360)
- Singapore(1)
- United States(69)
- United Kingdom(20)
- Canada(6)
- France(5)
- Germany(19)
- Europe(3)
- Italy(8)
- South Korea(1)
- Ireland(1)
- Switzerland(3)
- Japan(3)
- Czech Republic(3)
- Poland(4)
- Spain(6)
- Venezuela(1)
- Mexico(2)
- Belgium(3)
- The Netherlands(2)
- Brazil(4)
- United Arab Emirates(1)
- Egypt(1)
- Austria(1)
- Jordan(1)
- Slovenia(1)
- Philippines(1)
- Malaysia(1)
Company Type
Properties
- Melting point:
- 147-149°C
- Boiling point:
- 501.14°C (rough estimate)
- Density
- 1.1095 (rough estimate)
- refractive index
- 1.5940 (estimate)
- storage temp.
- 2-8°C
- solubility
- Soluble in chloroform, DMSO, DMF and alcohols
- pka
- pKa 4.7(EtOH 50%aq ) (Uncertain)
- form
- Solid
- color
- White to Almost white
- Water Solubility
- <10mg/L(25 ºC)
- λmax
- 556nm(Phosphate buffer sol.)(lit.)
- Merck
- 14,2417
- InChI
- InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H
- InChIKey
- VNFPBHJOKIVQEB-UHFFFAOYSA-N
- SMILES
- C1N(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CN=1
Safety Information
- Symbol(GHS)
GHS07,GHS09
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H410
- Precautionary statements
- P264-P270-P273-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-36/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- NI4377000
- HS Code
- 29332900
- Toxicity
- LD50 in male mice, rats (mg/kg): 923, 708 orally (Tettenborn)
Use
Clotrimazole formally also is an imidazole derivative because of the presence of an imidazole ring in its structure. It is believed that, like miconazole, econazole, and other “pure” representatives of the imidazole class, it also inhibits the biosynthesis of ergosterin in the cytoplasmatic membrane of fungi. In terms of pharmacological action, clotrimazole is very similar to miconazole. It has a broad spectrum of antifungal activity. It is effective with respect to dermatophytes, and it also has an antimicrobial effect against streptococci and staphylococci. It is also effective with respect to trichomonases. It is very widely used, both externally and vaginally for treating superficial infections.
122 India supplier list of "Clotrimazole"
- Product Name:CLOTRIMAZOLE IP/USP
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 25kg
- Company Type: Manufacturer
- Country/Region: Ahmedabad,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Clotrimazole IP/BP/EP/USP
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Uttar Pradesh,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: NaviMumbai,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Clotrimazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:CLOTRIMAZOLE
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA