Amodiaquine
Amodiaquine
- CAS:
- 86-42-0
- MF:
- C20H22ClN3O
- MW:
- 355.86
Suppliers by country/region
Company Type
Properties
- Melting point:
- 208°C
- Boiling point:
- 478.0±45.0 °C(Predicted)
- Density
- 1.258
- storage temp.
- -20°C Freezer
- solubility
- DMSO (Slightly, Sonicated), Methanol (Slightly)
- form
- Solid
- pka
- 9.43±0.50(Predicted)
- color
- Pale Yellow to Light Yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- Toxicity
- LD50 oral in mouse: 550mg/kg
Use
Amodiaquine, an antimalarial agent related to chloroquine, was introduced over 40 years ago for the treatment and prophylaxis of malaria. The drug was voluntarily withdrawn in the United Kingdom in 1975 for commercial reasons but was subsequently reintroduced in 1985 to meet the medical demand for an antimalarial drug to deal with the rapid spread of chloroquine-resistant falciparum malaria in Asia and Africa. By 1986 a significant number of cases of agranulocytosis associated with prophylactic use, some of which were fatal, had been reported there and it has been estimated that the frequency of this risk is of the order of 1:2,000. Although most cases occurred when amodiaquine had been used in combination with other antimalarials, the major manufacturer decided to withdraw the prophylactic indication worldwide following discussions with experts. Preparations remain available for the treatment of acute attacks of malaria which involves only a short period of exposure to the drug. (Reference: (WHODI) WHO Drug Information, 1, 5, 1987)
13 India supplier list of "Amodiaquine"
- Product Name:AMODIQUINE BASE
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Amodiaquine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Amodiaquine Base
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Amodiaquine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Amodiaquine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Amodiaquine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Amodiaquine 98.00%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.086210
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Amodiaquine
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Amodiaquine
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Amodiaquine
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA