Budesonide
Budesonide
- CAS:
- 51333-22-3
- MF:
- C25H34O6
- MW:
- 430.53
Suppliers by country/region
- India(100)
- CHINA(254)
- United States(48)
- Canada(9)
- United Kingdom(18)
- Germany(10)
- Europe(1)
- France(7)
- Russia(1)
- South Korea(2)
- Japan(1)
- Mexico(1)
- Philippines(1)
- Israel(2)
- Italy(7)
- Czech Republic(1)
- South Africa(1)
- Brazil(2)
- Belgium(2)
- The Netherlands(4)
- Poland(1)
- Spain(2)
- United Arab Emirates(1)
- Austria(1)
- Greece(1)
- Switzerland(1)
- Malaysia(2)
- Nepal(1)
Company Type
Properties
- Melting point:
- 221-232°C (dec.)
- alpha
- D25 +98.9° (c = 0.28 in methylene chloride)
- Boiling point:
- 464.79°C (rough estimate)
- Density
- 1.1046 (rough estimate)
- refractive index
- 1.4593 (estimate)
- storage temp.
- Store at RT
- solubility
- Practically insoluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).
- form
- powder
- pka
- 12.87±0.10(Predicted)
- color
- White to Off-White
- Water Solubility
- 21.53mg/L(temperature not stated)
- Merck
- 14,1468
- BCS Class
- 2
- InChIKey
- VOVIALXJUBGFJZ-KWVAZRHASA-N
Safety Information
- Symbol(GHS)
GHS08,GHS07
- Signal word
- Danger
- Hazard statements
- H361-H332-H317-H334-H312
- Precautionary statements
- P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P201-P202-P281-P308+P313-P405-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501-P261-P285-P304+P341-P342+P311-P501
- Hazard Codes
- Xn
- Risk Statements
- 40-36/37/38-20/21/22
- Safety Statements
- 22-36-26
- WGK Germany
- 3
- RTECS
- TU3723000
- HS Code
- 29372900
- Toxicity
- LD50 oral in rat: > 3200mg/kg
Use
Budesonide, 16α,17-[butylidenebis-(oxy)]-11β,21-dihydroxypregna-1,4-diene-3, 20-dione (Entocort), in oral capsules is used to treat Crohn disease. Theaffinity for the GC is approximately 200-fold greater than thatof hydrocortisone and 15-fold greater than that of prednisolone.Budesonide is a mixture of epimers, with the 22Rform having twice the affinity for the GR of the S epimer.This GC is metabolized by CYP3A4, and its levels can be increasedin the presence of potent CYP3A4 inhibitors.Budesonide is also used in an inhaled formulation for thetreatment of asthma.
100 India supplier list of "Budesonide"
- Product Name:Budesonide
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Budesonide API
- Products Intro:Purity: 98% | Package: 50 MG; 100 MG; 250 MG ; 5 GM
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Budesonide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Madhya Pradesh,INDIA
- Product Name:Budesonide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:BUDESONIDE
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Budesonide Reference Standard
- Products Intro:Purity: 98% | Package: 25mg; 50mg;100mg and 1 g
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Budesonide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Budesonide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Budesonide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Budesonide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Haryana,INDIA