Buspirone
Buspirone
- CAS:
- 36505-84-7
- MF:
- C21H31N5O2
- MW:
- 385.5
Suppliers by country/region
Company Type
Properties
- Melting point:
- 105-107 °C(Solv: ethyl acetate (141-78-6))
- Boiling point:
- 511.93°C (rough estimate)
- Density
- 1.1527 (rough estimate)
- refractive index
- 1.7600 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- form
- Solid
- pka
- pKa 7.60±0.01(H2O t=25.0 I=0.1(NaCl)) (Uncertain)
- color
- White to off-white
- BCS Class
- 1
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P321-P330-P405-P501
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- CL9915000
Use
The initial compound in this series, buspirone (BuSpar), hasanxiolytic and antidepressant activities and is a partial5-HT1A agonist. Its anxiolytic activity is reportedly causedby its ability to diminish 5-HT release (via 5-HT1A agonism).High short-term synaptic levels of 5-HT are characteristic ofanxiety. Also, because it is a partial agonist, it can stimulatepostsynaptic receptors when 5-HT levels are low in thesynapse, as is the case in depression. Several other spironesare in development as anxiolytics and antidepressants.
3 India supplier list of "Buspirone"
- Product Name:Buspirone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Buspirone
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Bangalore,INDIA
- Product Name:Buspirone
- Products Intro:Brand:clearsynth | Product Number:CS-O-06173
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Buspirone
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Buspirone
- Products Intro:Brand:pharmaffiliates | Product Number:PA021980000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Buspirone
- Products Intro:Purity: 99% | Package: 25KG
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$0.00/ 25KG
- Product Name:36505-84-7 Buspirone
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:buspirone
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Buspirone
- Products Intro:Purity: 0.99
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Fine Chemical,API,Raw Material,Pharmaceutical Compounds,Others