CARBENICILLIN INDANYL SODIUM
CARBENICILLIN INDANYL SODIUM
- CAS:
- 26605-69-6
- MF:
- C26H26N2O6S.Na
- MW:
- 0
Suppliers by country/region
Properties
- Melting point:
- 207-213°
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Water (Slightly, Heated, Sonicated)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic, Temperature Sensitive
Safety Information
- HS Code
- 2941106000
Use
Carbenicillin indanyl sodium has been shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic. Efforts to obtain orally active forms of carbenicillin led to theeventual release of the 5-indanyl ester carbenicillin indanyl,6-[2-phenyl-2-(5-indanyloxycarbonyl)acetamido]penicillanicacid (Geocillin), in 1972. Approximately 40% of theusual oral dose of indanyl carbenicillin is absorbed. After absorption,the ester is hydrolyzed rapidly by plasma and tissueesterases to yield carbenicillin. Thus, although the highlylipophilic and highly protein-bound ester has in vitro activitycomparable with that of carbenicillin, its activity in vivo isdue to carbenicillin. Indanyl carbenicillin thus provides anorally active alternative for the treatment of carbenicillinsensitivesystemic and urinary tract infections caused byPseudomonas spp., indole-positive Proteus spp., and selectedspecies of Gram-negative bacilli.Clinical trials with indanyl carbenicillin revealed a relativelyhigh frequency of GI symptoms (nausea, occasionalvomiting, and diarrhea). It seems doubtful that the highdoses required for the treatment of serious systemic infectionscould be tolerated by most patients. Indanyl carbenicillinoccurs as the sodium salt, an off-white, bitter powderthat is freely soluble in water. It is stable in acid. It should beprotected from moisture to prevent hydrolysis of the ester.
1 India supplier list of "CARBENICILLIN INDANYL SODIUM"
- Product Name:SodiumIndanylcarbinicillin
- Products Intro:Brand:clearsynth | Product Number:CS-T-61352
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:CARBENICILLIN INDANYL SODIUM
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:CarbenicillinIndanylSodium(1093500)
- Products Intro:Brand:pharmaffiliates | Product Number:PAUSP1093500
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:CARBENICILLIN INDANYL SODIUM USP/EP/BP
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CARBENICILLIN INDANYL SODIUM
- Products Intro:Purity: 99.9%|Package: 1g;1.1USD
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CARBENICILLIN INDANYL SODIUM
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:Carbenicillin indanyl sodium
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Active Pharmaceutical Ingredient (API),Insect Pheromone,Boronic Compounds,Material & Chemicals,Lipid Compounds
-
50mg$155.00500mg$1205.00
- Product Name:SodiumIndanylcarbinicillin
- Products Intro:Brand:trc-canada | Product Number:S635000
- Company Type: Trader
- Country/Region: CANADA
-
5MG$496.55
- Product Name:CARBENICILLIN INDANYL SODIUM
- Products Intro:Brand：Acccorporation | OriginalID：API0008939 | Purity：95.00%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:CARBENICILLIN INDANYL SODIUM (300 MG)
- Company Type: Trader
- Country/Region: UNITED STATES