CINOXACIN
CINOXACIN
- CAS:
- 28657-80-9
- MF:
- C12H10N2O5
- MW:
- 262.22
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Company Type
Properties
- Melting point:
- 261-262° (dec)
- Boiling point:
- 405.47°C (rough estimate)
- Density
- 1.3545 (rough estimate)
- refractive index
- 1.6660 (estimate)
- storage temp.
- 2-8°C
- solubility
- 1 M NaOH: soluble50mg/mL
- pka
- pKa 5.38(H2O t=25.0 I=0.025) (Uncertain)
- form
- solid
- color
- White to Off-White
- Stability:
- Hygroscopic
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- WGK Germany
- 2
- RTECS
- JI4640000
- Toxicity
- LD50 in rats (mg/kg): 4160 orally; 900 i.v. (Narama)
Use
1-Ethyl-1,4-dihydro-4-oxo[1,3]dioxolo[4,5g]cinnoline-3-carboxylic acid (Cinobac) is a close congener (isostere) ofoxolinic acid (no longer marketed in the United States) andhas antibacterial properties similar to those of nalidixic andoxolinic acids. It is recommended for the treatment of urinary tract infectionscaused by strains of Gram-negative bacteria susceptibleto these agents. Early clinical studies indicate that thedrug possesses pharmacokinetic properties superior to thoseof either of its predecessors. Thus, following oral administration,higher urinary concentrations of cinoxacin thanof nalidixic acid or oxolinic acid are achieved. Cinoxacinappears to be more completely absorbed and less proteinbound than nalidixic acid.
0 India supplier list of "CINOXACIN"
- Product Name:Cinoxacin
- Products Intro:Brand:sigma aldrich | Product Number:C8645
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Cinoxacin
- Products Intro:Brand:clearsynth | Product Number:CS-T-51144
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:1-ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
- Products Intro:Purity: 95% (Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
- Product Name:CINOXACIN
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CINOXACIN
- Products Intro:Purity: 98% | Package: 1g,10g,25g,500g,1kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 528-94-9,AMMONIUM SALICYLATE,Linolenic acid,463-40-1,931-36-2
- Product Name:Cinoxacin
- Products Intro:Purity: 98% | Package: 100mg, 250mg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Cinoxacin
- Products Intro:Purity: >=99% | Package: $58.9/50mg;$265.9/250mg;Bulk package | CustNote: 99%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:1-ethyl-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A819523
- Company Type: Reagent
- Country/Region: CHINA
-
1g$104.005g$379.00
- Product Name:Cinoxacin
- Products Intro:Brand: Sigma-Aldrich | Product Number: C8645
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof