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Clonazepam
Clonazepam
- CAS:
- 1622-61-3
- MF:
- C15H10ClN3O3
- MW:
- 315.71
Properties
- Melting point:
- 236.5-238.50C
- Boiling point:
- 524.5±50.0 °C(Predicted)
- Density
- 1.4592 (rough estimate)
- refractive index
- 1.6470 (estimate)
- Flash point:
- 11 °C
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, slightly soluble in alcohol and in methanol.
- pka
- 1.5, 10.5(at 25℃)
- form
- powder
- color
- light yellow
Safety Information
- Symbol(GHS)
GHS02,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H225-H301+H311+H331-H370
- Precautionary statements
- P210-P260-P280-P301+P310-P311
- Hazard Codes
- F,T
- Risk Statements
- 11-23/24/25-39/23/24/25
- Safety Statements
- 7-16-36/37-45-24/25-22
- RIDADR
- UN 1230 3/PG 2
- WGK Germany
- 2
- RTECS
- DF2100000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2933910000
- Toxicity
- LD50 orally in mice: >4000 mg/kg (Blum)
Use
Clonazepam has been found to be effective in the short- term treatment of anxiety disorders, including generalized anxiety disorder, social phobia, and panic disorder. Catatonia, alcohol withdrawal, and insomnia are other common indications supported by evidence. Clonazepam is also sometimes used for the treatment of acute mania, or psychosis- induced aggression and agitation (adjunctive treatment for bipolar disorder and schizophrenia).
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