CYCLOPIAZONIC ACID
CYCLOPIAZONIC ACID
- CAS:
- 18172-33-3
- MF:
- C20H20N2O3
- MW:
- 336.38
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Properties
- Melting point:
- 245-246°C
- Boiling point:
- 472.86°C (rough estimate)
- Density
- 1.2171 (rough estimate)
- refractive index
- 1.5700 (estimate)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 4.50±1.00(Predicted)
- color
- white to off-white
- Water Solubility
- Soluble in DMSO (100 mM), ethanol (5 mM), DMF (~20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H300
- Precautionary statements
- P264-P301+P310
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- UY8587000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29337900
- Toxicity
- chicken,LD50,oral,12mg/kg (12mg/kg),Poultry Science. Vol. 65(Suppl,
Use
Cyclopiazonic acid is a tremorigenic indole produced by several species of Aspergillus and Penicillium. Cyclopiazonic acid is a highly specific inhibitor of calcium ATPase of sarcoplasmic reticulum, altering calcium homeostasis and ATP-dependent calcium transport and resulting in the release of intracellular stored Ca2+ without increasing IP3.
0 India supplier list of "CYCLOPIAZONIC ACID"
- Product Name:CyclopiazonicAcid,Penicilliumcyclopium-CAS18172-33-3-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:239805 | Purity:Acell-permeable,reversibleinhibitorofsarcoplasmicreticulumCa2+-ATPasethatrelease
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Cyclopiazonic acid from Penicillium grisefulvum
- Products Intro:Purity: 98% | Package: $246.9/5mg;$424.9/10mg;$956.9/25mg;$1721.9/50mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
-
5mg$75.20
- Product Name:Cyclopiazonic Acid, Penicillium cyclopium - CAS 18172-33-3 - Calbiochem
- Products Intro:Brand: Sigma-Aldrich | Product Number: 239805 | Purity: A cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca2+-ATPase that releases Ca2+ from the same intracellular pools as Thapsigargin.
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: cof,mof