DBeQ
DBeQ
- CAS:
- 177355-84-9
- MF:
- C22H20N4
- MW:
- 340.42
Suppliers by country/region
Company Type
Properties
- Melting point:
- 149 °C
- Boiling point:
- 573.1±52.0 °C(Predicted)
- Density
- 1.259±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: ≥20mg/mL
- pka
- 7.78±0.30(Predicted)
- form
- powder
- color
- white to beige
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
- InChIKey
- QAIMUUJJAJBPCL-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H319
- Precautionary statements
- P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-36
- Safety Statements
- 26
- WGK Germany
- 3
- HS Code
- 2933.59.8000
Use
The ATPase p97 is an ubiquitin-selective chaperone known to play a critical role in the degradation of misfolded membrane and secretory proteins and has been linked to various cellular processes that require unfolding and disassembly of protein complexes. DBeQ is a selective, reversible, and ATP-competitive inhibitor of the ATPase p97 (Ki = 3.2 μM; IC50 = 1.5 μM). It does not exhibit activity when tested against a panel 170 protein kinases at concentrations as high as 15 μM. At 10 μM it blocks endoplasmic reticulum-associated degradation, impairing the autophagy pathway and promoting the activation of caspase-3 and -7 in cancer cells.[Cayman Chemical]
0 India supplier list of "DBeQ"
- Product Name:DBeQ
- Products Intro:Brand:sigma aldrich | Product Number:SML0031 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:DBeQ
- Products Intro:Brand:tcichemicals | Product Number:D5476
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:DBeQ
- Products Intro:Brand:ajchemicals | Product Number:JDH-28014 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:DBeQ
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:DBeQ
- Products Intro:Purity: >98% | Package: 50mg | CustNote: BOC Sciences also provides custom synthesis services for DBeQ.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:DBEQ
- Products Intro:Purity: 98% | Package: Package as requetsed
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Specialty chemical,UV Curing & Brightener,OLED Chemicals,CDMO SERVICES
- Product Name:DBEQ
- Products Intro:Purity: 0.99 | Package: Various Packaging; segregation
- Company Type: Service provider
- Country/Region: CHINA
- Product Name:DBeQ
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:DBeQ
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: DBeQ
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:DBEQ
- Products Intro:Package: 1g; 5g; 25g; 1kg; 5kg; 25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate