Epinastine
Epinastine
- CAS:
- 80012-43-7
- MF:
- C16H15N3
- MW:
- 249.31
Suppliers by country/region
Company Type
Properties
- Melting point:
- 205-208°
- Boiling point:
- 428.0±55.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO : ≥ 50 mg/mL (200.55 mM);Water : < 0.1 mg/mL (insoluble)
- pka
- 11.2(at 25℃)
- form
- Solid
- color
- White to off-white
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H302-H411-H372
- Precautionary statements
- P273-P280
Use
Epinastine hydrochloride, an orally active antihistaminic agent, was marketed in Japan for the treatment of bronchial asthma, allergic rhinitis, urticaria, eczema, dermatitis, and psoriasis vulgaris.Epinastine is one of the most effective peripherally acting histamine H1-receptor antagonists without sedative effects.In addition, it exhibits potent anti-PAF and anti-LT activity which may also contribute significantly to its antiallergic activity. Chronic epinastine has been reported to effectively inhibit airway hyper-responsiveness in rats. Potent inhibitory effects of epinastine on bronchoconstriction induced by histamine and bradykinin, but not by other chemical mediators, has also been reported. Studies have indicated that there are no significant differences in pharmacological properties among D-, L-, and racemic epinastine.
3 India supplier list of "Epinastine"
- Product Name:Epinastine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Tamil Nadu,INDIA
- Product Name:Epinastine
- Company Type: Reagent
- Country/Region: Karnataka,INDIA
- Product Name:Epinastine
- Products Intro:Purity: 99% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:Epinastine
- Products Intro:Purity: 99% | Package: 1g;1USD|10g;1USD|100g;1USD|1KG;1USD|25KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00-1.00 / 1g
- Product Name:epinastine
- Products Intro:Purity: 99% | Package: 25KG;USD
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
$0.00/ 25KG