Erythromycin Estolate
Erythromycin Estolate
- CAS:
- 3521-62-8
- MF:
- C52H97NO18S
- MW:
- 1056.39
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Properties
- Melting point:
- 135-140°C dec.
- Boiling point:
- 743℃
- Density
- 1.0053 (rough estimate)
- refractive index
- 1.6550 (estimate)
- Flash point:
- >110°(230°F)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- chloroform: soluble4.0ML, clear, colorless (200 mg + 4.0 mL Chloroform)
- form
- Solid
- pka
- 6.9(at 25℃)
- color
- white
- Water Solubility
- Freely soluble in organic solvents, practically insoluble in water /n
- Sensitive
- Light Sensitive
Safety Information
- Symbol(GHS)
GHS07,GHS08
- Signal word
- Danger
- Hazard statements
- H302-H317-H334
- Precautionary statements
- P261-P264-P280-P301+P312-P302+P352-P304+P340+P312
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-42/43-36/37/38
- Safety Statements
- 22-36-26
- WGK Germany
- 3
- RTECS
- KF5775000
- HS Code
- 29419000
- Toxicity
- LD50 orally in rats: >5000 mg/kg (Goldenthal)
Use
Erythromycin estolate, erythromycin propionate lauryl sulfate(Ilosone), is the lauryl sulfate salt of the 2＇-propionateester of erythromycin. Erythromycin estolate is acid stableand absorbed as the propionate ester. The ester undergoesslow hydrolysis in vivo. Only the free base binds to bacterialribosomes. Some evidence, however, suggests that theester is taken up by bacterial cells more rapidly than thefree base and undergoes hydrolysis by bacterial esteraseswithin the cells. The incidence of cholestatic hepatitis is reportedlyhigher with the estolate than with other erythromycinpreparations.Erythromycin estolate occurs as long needles that aresparingly soluble in water but soluble in organic solvents. administration for the treatment of serious infections,such as Legionnaires disease, or when oral administrationis not possible. Solutions are stable for 1 week whenrefrigerated.
73 India supplier list of "Erythromycin Estolate"
- Product Name:Erythromycin estolate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Erythromycin estolate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Erythromycin Estolate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Erythromycin estolate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Erythromycin estolate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Erythromycin estolate
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Erythromycin estolate
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Erythromycin estolate, 600ug/mg
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.040938
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Erythromycin Estolate
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Erythromycin 2'-propionate dodecyl sulfate
- Company Type: Trader
- Country/Region: New Delhi,INDIA