Foretinib (GSK1363089)
Foretinib (GSK1363089)
- CAS:
- 849217-64-7
- MF:
- C34H34F2N4O6
- MW:
- 632.65
Suppliers by country/region
Company Type
Properties
- Melting point:
- >98°C (dec.)
- Boiling point:
- 828.5±65.0 °C(Predicted)
- Density
- 1.372
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Ethanol (Slightly)
- form
- Yellow powder.
- pka
- 13.14±0.70(Predicted)
- color
- Pale Yellow to Yellow
Safety Information
- Symbol(GHS)
GHS08,GHS07
- Signal word
- Warning
- Hazard statements
- H373-H302
- Precautionary statements
- P260-P314-P501-P264-P270-P301+P312-P330-P501
Use
Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM in cell-free assays. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR. Phase 2.
1 India supplier list of "Foretinib (GSK1363089)"
- Product Name:Foretinib >95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.089159
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Foretinib
- Products Intro:Brand:clearsynth | Product Number:CS-EK-02762
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Foretinib
- Products Intro:Brand:ajchemicals | Product Number:JDH-30522 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Foretinib (XL-880)
- Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
- Product Name:Foretinib
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:Foretinib (GSK1363089)
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$2.00/ 1kg
- Product Name:foretinib
- Products Intro:Package: 250mg | CustNote: BOC Sciences also provides custom synthesis services for foretinib.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Foretinib (GSK1363089)
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:foretinib
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Foretinib (GSK1363089)
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA