Guanfacine
Guanfacine
- CAS:
- 29110-47-2
- MF:
- C9H9Cl2N3O
- MW:
- 246.09
Suppliers by country/region
Company Type
Properties
- Melting point:
- 227-230?C
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- Soluble in DMSO
- form
- Powder
- pka
- 11.92±0.46(Predicted)
- BCS Class
- 1
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P321-P330-P405-P501
Use
Guanfacine is more selective for 2-receptors than isclonidine. Their mechanism of action is the same as that ofclonidine. Differences between clonidine and its twoanalogs are seen in their elimination half-life values and intheir metabolism and urinary excretion patterns. The eliminationhalf-life of clonidine ranges from 20 to 25 hours,whereas that for guanfacine is about 17 hours. Guanabenzhas the shortest DOA of these three agents, with a half-lifeof about 6 hours. Clonidine and guanfacine are excretedunchanged in the urine to the extent of 60% and 50%,respectively. Very little of guanabenz is excreted unchangedin the urine.
2 India supplier list of "Guanfacine"
- Product Name:Guanfacine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Guanfacine
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:Guanfacine
- Products Intro:Brand:clearsynth | Product Number:CS-T-25721
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Guanfacine
- Products Intro:Brand:pharmaffiliates | Product Number:PA0745000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:guanfacine
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Guanfacine
- Products Intro:Purity: 99.0% | Package: 100g;1kg;5kg;25kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Guanfacine USP/EP/BP
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Guanfacine
- Products Intro:Purity: NLT 98% | CustNote: MC546722
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: 2432-11-3,1052686-50-6,2198-53-0,3769-42-4,83647-42-1
- Product Name:Guanfacine
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate
- Product Name:Guanfacine
- Products Intro:Purity: 98% | Package: $129.9/10mg;$267.9/25mg;$447.9/50mg;$790.9/100mg;$1580.9/250mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies