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Ibuprofen

Ibuprofen

CAS:
15687-27-1
MF:
C13H18O2
MW:
206.28

Properties

Melting point:
77-78 °C
alpha 
[α]D20 -1~+1°(c=1,C2H5OH)
Boiling point:
157 °C (4 mmHg)
Density 
1.0364 (rough estimate)
refractive index 
1.5500 (estimate)
Flash point:
9℃
storage temp. 
2-8°C
solubility 
Practically insoluble in water, freely soluble in acetone, in methanol and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides and carbonates.
pka
pKa 4.45± 0.04(H2O,t = 25±0.5,I=0.15(KCl))(Approximate)
form 
Crystalline Powder
color 
white to off-white
Water Solubility 
insoluble
Merck 
14,4881
BCS Class
2
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
HEFNNWSXXWATRW-UHFFFAOYSA-N
LogP
3.970

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H302-H319-H335
Precautionary statements 
P261-P264-P270-P271-P301+P312-P305+P351+P338
Hazard Codes 
Xn
Risk Statements 
22-63-51/53-39/23/24/25-23/24/25-11
Safety Statements 
36-61-36/37-45-16-7
HS Code 
29163920
Toxicity
LD50 in male mice, rats (mg/kg): 495, 626 i.p.; 1255, 1050 orally (Orzalesi)

Use

Ibuprofen (Advil, Motrin) is used as an analgesic and antipyretic as well as a treatment for rheumatoid arthritis and degenerative joint disease. The most frequently observed side effects are nausea, heartburn, epigastric pain, rash, and dizziness. Incidence of GI side effects is lower than with indomethacin.Visual changes and cross-sensitivity to aspirin have been reported. Ibuprofen inhibits COX-1 and COX-2 about equally. It decreases platelet aggregation, but the duration is shorter and the effect quantitatively lower than with aspirin. Ibuprofen prolongs bleeding times toward high normal value and should be used with caution in patients who have coagulation deficits or are receiving anticoagulant therapy.

146 India supplier list of "Ibuprofen"

  • Product Name:Ibuprofen
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: Maharashtra,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Manufacturer
  • Country/Region: Uttar Pradesh,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Uttar Pradesh,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Bangalore,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Telangana,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: Maharashtra,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 99% | Package: 1KG;INR
  • Company Type: Manufacturer
  • Country/Region: Bangalore,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Manufacturer
  • Country/Region: Maharashtra,INDIA
  • Product Name:Ibuprofen
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
  • Company Type: Reagent
  • Country/Region: Gujarat,INDIA

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