illudin S
illudin S
- CAS:
- 1149-99-1
- MF:
- C15H20O4
- MW:
- 264.32
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Properties
- Melting point:
- 124-126℃
- Boiling point:
- 327.55°C (rough estimate)
- Density
- 1.0583 (rough estimate)
- refractive index
- 1.4300 (estimate)
- storage temp.
- -20°C, Inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- A light yellow solid
- pka
- 12.50±0.70(Predicted)
- color
- Off-white to yellow
Safety Information
Use
Illudin S is potent antitumor sesquiterpene, first isolated from the fungus, Clitocybe illudens, in 1963. Illudin S is metabolically activated to reactive intermediates that bind DNA. The DNA damage appears to differ from that of other reactive metabolites. Importantly, illudin S exhibits in vitro and in vivo potency against multi-drug resistant tumors.
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