IWR-1-endo
IWR-1-endo
- CAS:
- 1127442-82-3
- MF:
- C25H19N3O3
- MW:
- 409.44
Suppliers by country/region
Company Type
Properties
- alpha
- -3.0～+3.0°(20℃/D)(c=0.1,CH3CN)
- Boiling point:
- 643.9±55.0 °C(Predicted)
- Density
- 1.425±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- DMSO: soluble5mg/mL, clear
- pka
- 11.88±0.43(Predicted)
- form
- Liquid
- color
- white to beige
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P280-P305+P351+P338
- WGK Germany
- 3
Use
IWR-1-endo act as inhibitors of Wnt response. It appear that IWR compounds induce stabilization of Axin proteins via a direct interaction, which is a part of the b-catenin destruction complex (consists of Apc, Axin, Ck1 and Gsk3b). Such compounds may be used in the treatment of Wnt protein signaling-related diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosi s.
0 India supplier list of "IWR-1-endo"
- Product Name:IWR-1
- Products Intro:Brand:sigma aldrich | Product Number:I0161 | Purity:≥98%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:IWR-1-endo
- Products Intro:Brand:ajchemicals | Product Number:JDH-31622 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:IWR-1
- Products Intro:Brand:clearsynth | Product Number:CS-T-30158
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:IWR-1-endo (Fandachem)
- Products Intro:Purity: As coa | Package: As request | CustNote: 1127442-82-3
- Company Type: Trader
- Country/Region: CHINA
- Product Name:IWR-1-endo
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:IWR-1-endo
- Products Intro:Purity: >98% | Package: 25mg | CustNote: BOC Sciences also provides custom synthesis services for IWR-1-endo.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:IWR-1-endo
- Products Intro:Purity: 99% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:IWR-1-endo
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:IWR-1
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: IWR-1
- Company Type: Trader
- Country/Region: CHINA
- Main Products: sarms
- Product Name:IWR-1-endo
- Products Intro:Purity: 0 | Package: 1g; 5g; 25g; 1kg; 5kg; 25kg | CustNote: 0
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmaceutical intermediate