KAHWEOL
KAHWEOL
- CAS:
- 6894-43-5
- MF:
- C20H26O3
- MW:
- 314.42
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Properties
- Melting point:
- 88-90℃
- Boiling point:
- 476.6±45.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMF:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
DMSO:18.17(Max Conc. mg/mL);57.77(Max Conc. mM)
Ethanol:5.0(Max Conc. mg/mL);0.64(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:5):0.02(Max Conc. mg/mL);0.06(Max Conc. mM)
- pka
- 14.43±0.40(Predicted)
- form
- White to off-white solid.
- color
- Off-white to light yellow
- LogP
- 3.380 (est)
Safety Information
Use
Kahweol is an antioxidant diterpene contained in unfiltered coffee. Kahweol behaves as an anti-inflammatory and anti-angiogenic compound with potential use in antitumoral therapies. Recent research have demonstrated the ability of Kahweol in inhibiting metastasis by modulating expressions of MMPs and VEGF via STAT3 inactivation.
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