LACOSAMIDE
LACOSAMIDE
- CAS:
- 175481-36-4
- MF:
- C13H18N2O3
- MW:
- 250.29
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Properties
- Melting point:
- 141-143?C
- alpha
- D23 +16.0° (c = 1 in CH3OH)
- Boiling point:
- 536.4±50.0 °C(Predicted)
- Density
- 1.120±0.06 g/cm3(Predicted)
- Flash point:
- 2℃
- storage temp.
- Refrigerator
- solubility
- DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 2 mg/ml
- form
- A crystalline solid
- pka
- 14.19±0.46(Predicted)
- InChI
- InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1
- InChIKey
- VPPJLAIAVCUEMN-GFCCVEGCSA-N
- SMILES
- C(NCC1=CC=CC=C1)(=O)[C@H](NC(C)=O)COC
Safety Information
- Symbol(GHS)
GHS02,GHS07
- Signal word
- Danger
- Hazard statements
- H225-H302+H312+H332-H319
- Precautionary statements
- P210-P280-P305+P351+P338
- Hazard Codes
- F,Xn
- Risk Statements
- 11-20/21/22-36
- Safety Statements
- 16-26-36/37
- RIDADR
- UN 1648 3 / PGII
- WGK Germany
- 2
- HS Code
- 2924296000
Use
Lacosamide is an anticonvulsant and analgesic compound used for the treatment of partial-onset seizures and neuropathic pain. It can also used for the treatment of status epilepticus. Its analgesic effect is mediated by its inhibitory effect on sodium channels, which leads to neural membrane depolarization. Its interaction with the collapsin-response mediator protein 2 (CRMP-2 alias DRP-2) may also facilitate the above process, although the detailed mechanism remains to be elucidated.?
115 India supplier list of "LACOSAMIDE"
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Hyderabad,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Lacosamide
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA