M344
M344
- CAS:
- 251456-60-7
- MF:
- C16H25N3O3
- MW:
- 307.39
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Properties
- Melting point:
- 161℃
- Density
- 1.137±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- White solid
- pka
- 9.48±0.20(Predicted)
- color
- white to beige
- Sensitive
- Light Sensitive
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P302+P352-P305+P351+P338-P321-P405-P501
- WGK Germany
- 3
- HS Code
- 2928.00.2500
Use
M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1. M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM).
0 India supplier list of "M344"
- Product Name:HistoneDeacetylaseInhibitorIII
- Products Intro:Brand:sigma aldrich | Product Number:382149 | Purity:TheHistoneDeacetylaseInhibitorIII,alsoreferencedunderCAS251456-60-7,controlstheb
- Company Type: Trader
- Country/Region: Bangalore,INDIA