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M344

M344

CAS:
251456-60-7
MF:
C16H25N3O3
MW:
307.39

Properties

Melting point:
161℃
Density 
1.137±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
White solid
pka
9.48±0.20(Predicted)
color 
white to beige
Sensitive 
Light Sensitive

Safety Information

Symbol(GHS) 

GHS07
Signal word 
Warning
Hazard statements 
H315-H319-H335
Precautionary statements 
P261-P302+P352-P305+P351+P338-P321-P405-P501
WGK Germany 
3
HS Code 
2928.00.2500

Use

M 344 is an inhibitor of histone deacetylases (HDACs), inhibiting maize HDAC (IC50 = 100 nM) as well as human HDAC1 (IC50 = 46 nM). It shows a three-fold selectivity for inhibition of HDAC6 over HDAC1. M 344 enhances the sensitivity of human squamous carcinoma cells to radiation and promotes cell cycle arrest and apoptosis in human endometrial cancer and ovarian cancer cells (ED50 = 2.3 μM).

0 India supplier list of "M344"

  • Product Name:HistoneDeacetylaseInhibitorIII
  • Products Intro:Brand:sigma aldrich | Product Number:382149 | Purity:TheHistoneDeacetylaseInhibitorIII,alsoreferencedunderCAS251456-60-7,controlstheb
  • Company Type: Trader
  • Country/Region: Bangalore,INDIA
  • Product Name:N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
  • Products Intro:Brand:clearsynth | Product Number:CS-T-27214
  • Company Type: Trader
  • Country/Region: Hyderabad,INDIA
  • Product Name:M344
  • Products Intro:Brand:ajchemicals | Product Number:JDH-31925 | Purity:98+%
  • Company Type: Trader
  • Country/Region: New Delhi,INDIA
  • Product Name:4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide
  • Products Intro:Brand:tcichemicals | Product Number:D4188
  • Company Type: Reagent
  • Country/Region: New Delhi,INDIA
  • Product Name:M344
  • Products Intro:Purity: 0.99 | Package: 5MG;10MG;50MG;100MG,1G,5G
  • Company Type: Reagent
  • Country/Region: CHINA

    $1.00/ 1g

  • Product Name:M344
  • Products Intro:Purity: 99% | Package: 1g;1USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:M344
  • Products Intro:Purity: 98% | Package: Package as requetsed
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Specialty chemical,UV Curing & Brightener,OLED Chemicals,CDMO SERVICES
  • Product Name:M344
  • Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide
  • Products Intro:Purity: 98% | Package: 1g,10g,25g,500g,1kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 528-94-9,AMMONIUM SALICYLATE,Linolenic acid,463-40-1,931-36-2
  • Product Name:M344 HDAC inhibitor M-344 Histone Deacetylase Inhibitor III
  • Products Intro:Purity: 99% | Package: 5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: sarms

M344 Related Search:

CyclicdimethylpolysiloxaneM344
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