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MEPHOBARBITAL

MEPHOBARBITAL

CAS:
115-38-8
MF:
C13H14N2O3
MW:
246.26

Properties

Melting point:
1760C
Boiling point:
389.26°C (rough estimate)
Density 
1.1855 (rough estimate)
refractive index 
1.6450 (estimate)
Flash point:
11 °C
storage temp. 
Controlled Substance, -20°C Freezer
solubility 
Practically insoluble in water, very slightly soluble in ethanol (96 per cent).
pka
7.99±0.10(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
0.15g/L(20 ºC)

Safety Information

Symbol(GHS) 

GHS02,GHS06,GHS08
Signal word 
Danger
Hazard statements 
H225-H301+H311+H331-H370
Precautionary statements 
P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
Hazard Codes 
Xn,T,F
Risk Statements 
22-39/23/24/25-23/24/25-11
Safety Statements 
36/37/39-45-36/37-16-7
RIDADR 
3249
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2933530000
Toxicity
cat,LD50,oral,230mg/kg (230mg/kg),Drugs in Japan Vol. 6, Pg. 851, 1982.

Use

Mephobarbital, 3-methyl-5-ethyl-5-phenylbarbituric acid (metharbital), is metabolicallyN-demethylated to phenobarbital, which many consider toaccount for almost all of the activity. Its principal use is asan anticonvulsant.

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PhenobarbitalBarbituric acidMEPHOBARBITALBenzobarbital
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