METHAPYRILENE
METHAPYRILENE
- CAS:
- 91-80-5
- MF:
- C14H19N3S
- MW:
- 261.38576
Suppliers by country/region
Properties
- Melting point:
- 25°C
- Boiling point:
- bp0.45 125-135°; bp3 173-175°
- Density
- 1.1388 (rough estimate)
- refractive index
- nD25 1.5842 (also reported as 1.5835)
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- DMSO (Sparingly), Methanol (Slightly)
- form
- Oil
- pka
- pKa 3.02 ± 0.05;8.24± 0.11(H2O,t undefined,I=0.30(NaCl)) (Uncertain)
- color
- Colourless to Light Yellow
- Water Solubility
- 601.2mg/L(30 ºC)
- Stability:
- Stable. Incompatible with strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301
- Precautionary statements
- P264-P270-P301+P310-P321-P330-P405-P501
- RIDADR
- 1851
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- LD50 in mice, guinea pigs (mg/kg): 182.2 ±12.8, 374.9 ±34.5 orally; in mice (mg/kg): 19.85 ±0.69 i.v. (Lee)
Use
Methapyrilene, an antihistamine with moderate sedative activity, was introduced in 1947 for the treatment of various allergic conditions and was subsequently incorporated in many over-the-counter sleeping aids. In the early 1970s it was identified as a carcinogen in rats and, although there was no direct evidence that it constitutes a health hazard to man, it was withdrawn in many countries. (Reference: (WHODI) WHO Drug Information, 2, 4, 1979)
0 India supplier list of "METHAPYRILENE"
![](/images/pro-3.jpg)
- Product Name:Methapyrilene
- Products Intro:Brand:pharmaffiliates | Product Number:PA132060000
- Company Type: Trader
- Country/Region: Haryana,INDIA
![](/images/pro-3.jpg)
-
5MG$495.56
- Product Name:METHAPYRILENE
- Products Intro:Brand:Acccorporation | OriginalID:API0008711 | Purity:95.00%
- Company Type: Trader
- Country/Region: UNITED STATES
![](/images/pro-3.jpg)
- Product Name:METHAPYRILENE
- Company Type: Trader
- Country/Region: UNITED STATES
![](/images/pro-3.jpg)
- Product Name:METHAPYRILENE
- Products Intro:Purity: 98% | Package: 1g
- Company Type: Trader
- Country/Region: CHINA