MG-115
MG-115
- CAS:
- 133407-86-0
- MF:
- C25H39N3O5
- MW:
- 461.59
Suppliers by country/region
Properties
- Boiling point:
- 678.8±55.0 °C(Predicted)
- Density
- 1.082±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- powder
- pka
- 11.14±0.46(Predicted)
- color
- white
Safety Information
- WGK Germany
- 3
Use
(S)-MG115 is a potent and reversible proteasome inhibitor, targeting the chymotryptic site on the 20S particle (Ki = 21 nM). It reduces the degradation of ubiquitin-conjugated proteins in extracts. (S)-MG115 also blocks the degradation of long- and short-lived proteins in intact cells as well as the proteolytic generation of diverse proteins, including NF-κB, antigens, and p53. Proteasome inhibitors, including (S)-MG115, can induce a heat shock response and apoptosis, particularly in cancer cells.[Cayman Chemical]
0 India supplier list of "MG-115"
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- Product Name:MG-115-CAS133407-86-0-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:474780 | Purity:Potentreversibleproteasomeinhibitor(Ki=21nMand35nMfor20Sand26Sproteasome,respect
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:MG-115
- Products Intro:Purity: >=95% | Package: $119.9/1mg;$266.9/5mg;$424.9/10mg;$956.9/25mg;$1721.9/50mg;$3098.9/100mg;Bulk pa | CustNote: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies