Mitomycin C
Mitomycin C
- CAS:
- 50-07-7
- MF:
- C15H18N4O5
- MW:
- 334.33
Suppliers by country/region
Company Type
Properties
- Melting point:
- 360 °C
- Boiling point:
- 471.14°C (rough estimate)
- Density
- 1.2238 (rough estimate)
- refractive index
- 1.6800 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
- form
- powder
- pka
- pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
- color
- blue-gray
- PH
- pH (0.5 g/l, 25℃ : )5.0～7.0
- Water Solubility
- soluble
- Merck
- 14,6215
- BRN
- 7231816
- Stability:
- Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H300-H351
- Precautionary statements
- P201-P202-P264-P270-P280-P301+P310
- Hazard Codes
- T,Xn,T+
- Risk Statements
- 25-40-22-45-26/27/28
- Safety Statements
- 36/37-45-28A-28-53-22
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- CN0700000
- F
- 8-10
- TSCA
- Yes
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29419090
- Toxicity
- LD50 i.v. in mice: 5 mg/kg (Wakaki); also reported as 9 mg/kg (Kinoshita)
Use
Mitomycin C (MMC), an antineoplastic antibiotic derived from Streptomyces caespitosus or Streptomyces lavendulae, is a cell cycle-specific alkylating agent, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.
6 India supplier list of "Mitomycin C"
- Product Name:Mitomycin C
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:MitomycinCfromStreptomycescaespitosus
- Products Intro:Brand:sigma aldrich | Product Number:M0440 | Purity:≥970μg/mg(USPXXIV)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Mitomycin C 98% (HPLC)
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.037347
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Mitomycin
- Products Intro:Brand:synzeal | Product Number:103577449
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:MitomycinC
- Products Intro:Brand:clearsynth | Product Number:CS-DE-00017
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Mitomycin
- Company Type: Reagent
- Country/Region: Nagpur,INDIA
- Product Name:MITOMYCIN
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Ametycin
- Products Intro:Brand:tcichemicals | Product Number:M2320
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Mitomycin
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:Mitomycinc
- Products Intro:Brand:ajchemicals | Product Number:JDH-67769 | Purity:95%
- Company Type: Trader
- Country/Region: New Delhi,INDIA