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MUSCIMOL

MUSCIMOL

CAS:
2763-96-4
MF:
C4H6N2O2
MW:
114.1

Properties

Melting point:
175-176°C
Boiling point:
213.59°C (rough estimate)
Density 
1.291
refractive index 
1.4487 (estimate)
storage temp. 
2-8°C
solubility 
ethanol: 1 mg/mL
pka
12.19±0.40(Predicted)
form 
powder
color 
white to off-white
Water Solubility 
Soluble in water (10 mg/ml), methanol, ethanol, 0.05 M HCl (20 mg/ml), DMSO (sparingly soluble), DMF (sparingly soluble), and PBS (pH 7.2) (10 mg/ml).
Merck 
13,6336
BRN 
1618960
Stability:
Hygroscopic, Store in Freezer at -20°C

Safety Information

Symbol(GHS) 

GHS06
Signal word 
Danger
Hazard statements 
H300-H336
Precautionary statements 
P261-P264-P270-P271-P301+P310-P304+P340+P312
Hazard Codes 
T
Risk Statements 
25
Safety Statements 
22-36/37/39-45
RIDADR 
UN 1544 6.1/PG 2
WGK Germany 
3
RTECS 
NY3345000
3-10
TSCA 
Yes
HazardClass 
6.1(a)
PackingGroup 
II
HS Code 
29349990
Toxicity
LD50 in mice (mg/kg): 3.8 s.c., 2.5 i.p.; in rats (mg/kg): 4.5 i.v., 45 orally (Theobald)

Use

Muscimol is a toxic alkaloid of poisonousmushroom species, producing neurologicaction. It is a potent depressant of thecentral nervous system. The adverse healtheffects from its ingestion include sleep,hallucination, distorted perceptions, andvomiting.LD50 value, oral (mice): 17 mg/kgLD50 value, intraperitoneal (mice): 2.5 mg/kg.

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