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N,O-Bis(trimethylsilyl)acetamide

N,O-Bis(trimethylsilyl)acetamide

CAS:
10416-59-8
MF:
C8H21NOSi2
MW:
203.43

Properties

Melting point:
24 °C
Boiling point:
71-73 °C35 mm Hg(lit.)
Density 
0.832 g/mL at 20 °C(lit.)
vapor pressure 
10 hPa (50 °C)
refractive index 
n20/D 1.417(lit.)
Flash point:
53 °F
storage temp. 
Store below +30°C.
solubility 
Miscible with many nonpolar and polar aprotic solvents.
pka
5.82±0.50(Predicted)
form 
Crystalline Powder, Crystals and/or Chunks
Specific Gravity
0.832
color 
Light yellow or beige to brown
Sensitive 
Moisture Sensitive
Hydrolytic Sensitivity
7: reacts slowly with moisture/water
BRN 
1306669

Safety Information

Symbol(GHS) 

GHS02,GHS05,GHS07
Signal word 
Danger
Hazard statements 
H226-H302-H314
Precautionary statements 
P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes 
C,Xn,F
Risk Statements 
10-14-22-34-40-20/21/22-11
Safety Statements 
26-36/37/39-45-7/8-43A-36-30-23-16-7/9
RIDADR 
UN 2920 8/PG 2
WGK Germany 
3
RTECS 
AK3000000
10-21
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29310095
Toxicity
LD50 orally in Rabbit: 1580 mg/kg

Use

Clear to yellowish clear liquid liquid which is soluble in many nonpolar and polar aprotic solvents. The trimethylsilyl group is a frequently utilized monofunctional blocking group for protic organic and inorganic materials. As it eliminated during the silylation is neutral acetamide, N,O-Bis(trimethylsilyl)acetamide can be preferably used for substrates which are acid- or base-sensitive. N,O-bis(trimethylsilyl)-acetamide is an effective silylating agent. It is used in the pharmaceutical and in the chemical industry. Typically the silylating reaction with BSA results in neutral by-products only.

26 India supplier list of "N,O-Bis(trimethylsilyl)acetamide"

  • Product Name:N,O-Bis(trimethylsilyl)acetamide, 95%
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:BIS (TRIMETHYL SILYL) ACETAMIDE
  • Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:N,O-Bis-(trimethylsilyl)-acetamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Reagent
  • Country/Region: INDIA
  • Product Name:N,O-Bis-(trimethylsilyl)-acetamide
  • Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:N,O-Bis(trimethylsilyl)acetamide
  • Products Intro:Brand:sigma aldrich | Product Number:1.09649 | Purity:forgaschromatography
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:N,O-BIS-(TRIMETHYLSILYL) ACETAMIDE 97%
  • Products Intro:Brand:Glrinnovations | OriginalID:GLRBULK438
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:"N,O-Bis(trimethylsilyl)acetamide"
  • Products Intro:Brand:clearsynth | Product Number:CS-O-10667
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:trimethylsilyl(1E)-N-trimethylsilylethanimidate
  • Products Intro:Brand:thermofisher.in | Product Number:156460011 | Purity:95%
  • Company Type: Trader
  • Country/Region: INDIA
  • Product Name:N,o-Bis(trimethyl Silyl)acetamide
  • Company Type: Reagent
  • Country/Region: INDIA
  • Product Name:N,O-Bis(trimethylsilyl)acetamide
  • Company Type: Reagent
  • Country/Region: INDIA

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