OKADAIC ACID
OKADAIC ACID
- CAS:
- 78111-17-8
- MF:
- C44H68O13
- MW:
- 805
Suppliers by country/region
Company Type
Properties
- Melting point:
- 164-166 °C
- alpha
- D20 +21° (c = 0.33 in CHCl3); D25 +25.4° (c = 0.24 in CHCl3)
- Boiling point:
- 672.95°C (rough estimate)
- Density
- 1.0795 (rough estimate)
- refractive index
- 1.5940 (estimate)
- storage temp.
- -20°C
- solubility
- DMSO: ≥1 mg/mL
- form
- translucent film
- pka
- 3.87±0.16(Predicted)
- color
- translucent
- Water Solubility
- It is soluble in ethanol (25 mg/ml), DMSO (25 mg/ml), methanol (<1 mg/ml), chloroform, acetone, ethyl acetate, DMF, and dimethylsulfoxide. Insoluble in water, unless first dissolved in organic solvents, such as DMSO or ethanol.
- Merck
- 13,6891
- Stability:
- Stable. Light and heat-sensitive. Combustible. Incompatible with strong oxidizing agents.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H301+H311+H331-H315
- Precautionary statements
- P280-P301+P310+P330-P302+P352+P312-P304+P340+P311
- Hazard Codes
- T
- Risk Statements
- 23/24/25-38
- Safety Statements
- 26-36/37-45
- RIDADR
- UN 3462 6.1/PG 1
- WGK Germany
- 3
- RTECS
- AA8227800
- F
- 10
- HazardClass
- 6.1(a)
- PackingGroup
- II
- HS Code
- 29321900
- Toxicity
- LD50 i.p. in mice: 192 mg/kg (Shibata)
Use
Okadaic acid is a widely distributed marine toxin produced by several phytoplanktonic species and responsible for diarrheic shellfish poisoning in humans. At the molecular level, Okadaic acid is a pot ent and specific inhibitor of various types of serine/threonine protein phosphatases. Due to this enzymatic inhibition, Okadaic acid was reported to induce numerous alterations in relevant cellular ph ysiological processes, including metabolic pathways such as glucose uptake, lipolysis and glycolysis, heme metabolism and glycogen and protein synthesis.
0 India supplier list of "OKADAIC ACID"
- Product Name:OkadaicAcid,Prorocentrumsp.-CAS78111-17-8-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:495604 | Purity:OkadaicAcid,CAS78111-17-8,isahighlypotentinhibitorofproteinphosphatase1(IC??=10-
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:(2R)-3-[(2S,6R,8S,11R)-2-[(E)-4-[(2R,4R,4aS,6R,8aR)-4-hydroxy-2-[(1S,3S)-1-hydroxy-3-[(2R,3R,6S)-3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl]butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5''-oxolane]-2''-yl]but-3-en-2-yl]-11-hydroxy-4-
- Products Intro:Brand:thermofisher.in | Product Number:ALF-J60155-EXG | Purity:98%
- Company Type: Trader
- Country/Region: Maharashtra,INDIA