OLIGOMYCIN C
OLIGOMYCIN C
- CAS:
- 11052-72-5
- MF:
- C45H74O10
- MW:
- 775.06
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Properties
- Boiling point:
- 876.2±65.0 °C(Predicted)
- Density
- 1.091 g/cm3
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- White to off-white powder.
- pka
- 13.49±0.70(Predicted)
- Merck
- 13,6902
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P271
- Hazard Codes
- Xn
- Risk Statements
- 22
- RIDADR
- 2811
- RTECS
- RK3335000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 2941900000
- Toxicity
- LD50 ipr-mus: 8300 mg/kg JACSAT 80,6092,1958
Use
Oligomycin C, a minor component of the oligomycin complex isolated from selected strains of Streptomyces, is an inhibitor of mitochondrial F1F0-ATPase. It makes cells more susceptible to cell death, and also leads to a switch in the death mode from apoptosis to necrosis.
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