Pantoprazole
Pantoprazole
- CAS:
- 102625-70-7
- MF:
- C16H15F2N3O4S
- MW:
- 383.37
Suppliers by country/region
Company Type
Properties
- Melting point:
- 139-140° (dec)
- Boiling point:
- 586.9±60.0 °C(Predicted)
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
- pka
- pKa1 3.92; pKa2 8.19(at 25℃)
- form
- Solid
- color
- Off-White to Pale Orange
- BCS Class
- 3
- InChI
- InChI=1S/C16H15F2N3O4S/c1-23-13-5-6-19-12(14(13)24-2)8-26(22)16-20-10-4-3-9(25-15(17)18)7-11(10)21-16/h3-7,15H,8H2,1-2H3,(H,20,21)
- InChIKey
- IQPSEEYGBUAQFF-UHFFFAOYSA-N
- SMILES
- C1(S(CC2=NC=CC(OC)=C2OC)=O)NC2=CC(OC(F)F)=CC=C2N=1
- CAS DataBase Reference
- 102625-70-7(CAS DataBase Reference)
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302+H312+H332
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-37/38-41-48
- Safety Statements
- 22-26-36/37/39-45
- Hazardous Substances Data
- 102625-70-7(Hazardous Substances Data)
Use
Pantoprazole, an irreversible proton pump inhibitor, reached its first market worldwide in Germany for acute treatment of gastric and duodenal ulcers and gastroesophageal reflux disease. Proton pump inhibitors are more effective than other strategies in inhibiting acid secretion since they function at the final step of acid production, therefore, provide superior symptom relief and healing in all acid related diseases. As the third substituted benzimidazole proton pump inhibitor marketed, pantoprazole not only has superior ulcer-preventing effect but also is more potent than omeprazole in healing acetic acid-induced gastric and duodenal ulcers with extremely low acute toxicity. The mechanism of action for this class of compounds has been suggested to be mediated via the protonated form of the molecule which selectively reacts with cysteines present on the extracytoplasmic face of the enzyme to form covalent disulfide bonds.
21 India supplier list of "Pantoprazole"
- Product Name:Pantoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Mumbai,INDIA
- Product Name:Pantoprazole EC Pellets
- Products Intro:Purity: 98% | Package: 3MT
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Pantoprazole
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Pantoprazole 5-(difluoromethoxy)-2-(((3,4-dimethoxypyridin-2- yl)methyl)sulfinyl)-1H-benzo[d]imidazole
- Products Intro:Purity: 96% | Package: 25 mg, 50 mg , 100mg or 500 mg
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA