perlapine
perlapine
- CAS:
- 1977-11-3
- MF:
- C19H21N3
- MW:
- 291.39
Suppliers by country/region
Company Type
Properties
- Melting point:
- 136-138°
- Boiling point:
- 423.4°C (rough estimate)
- Density
- 1.0521 (rough estimate)
- refractive index
- 1.6080 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 5 mg/ml
- form
- A crystalline solid
- pka
- 8.00±0.20(Predicted)
- color
- White
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302
- Precautionary statements
- P264-P270-P301+P312-P330-P501
- Toxicity
- LD50 in male, female mice, rats (mg/kg): 61, 61, 60, 66 i.v.; 250, 300, 480, 420 s.c., 270, 280, 660, 720 orally (Yokotani)
Use
Perlapine is an atypical neuroleptic that blocks dopamine and serotonin (5-HT) receptors (Kis = 60, 30, and 30 nM for D2, D4, and 5-HT2A, respectively). Perlapine is also an agonist for hM3Dq, a designer receptor exclusively activated by designer drugs (DREADD) derived from the human muscarinic acetylcholine M3 receptor that activates neuronal firing. Perlapine displays >10,000-fold selectivity for hM3Dq over hM3.
0 India supplier list of "perlapine"
- Product Name:Perlapine
- Products Intro:Purity: NLT 98% | CustNote: MC537090
- Company Type: Manufacturer
- Country/Region: CHINA
- Product Name:Perlapine
- Products Intro:Package: 100 mg；500 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
-
1 mg$45.005 mg$95.0010 mg$140.00
- Product Name:Perlapine
- Products Intro:Brand: Caymanchem | Product Number: 17756 | Purity: ≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
-
10 mg$159.0050 mg$669.00
- Product Name:6-(4-Methyl-1-piperazinyl)-11H-dibenz[b,e]azepine
- Products Intro:Brand: Tocris Bioscience | Product Number: 5549 | Purity: ≥99% (HPLC)
- Company Type: Trader
- Country/Region: UNITED KINGDOM
- Product Name:Perlapine
- Products Intro:Brand：dcchemicals | Product Number：DC20708 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Perlapine
- Products Intro:Brand：csnpharm | Product Number：CSN24541
- Company Type: Trader
- Country/Region: UNITED STATES
-
1mg$123.00
- Products Intro:Brand:1pchem | Product Number:1P00AKPE | Purity:≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
-
10mg$289.00
- Product Name:Perlapine
- Products Intro:Brand：aksci | Product Number：1416CA
- Company Type: Trader
- Country/Region: UNITED STATES
-
1mg$55.0010mg$150.00
- Product Name:Perlapine
- Products Intro:Brand:trc-canada | Product Number:N900420
- Company Type: Trader
- Country/Region: CANADA
-
20MG$238.00
- Product Name:PERLAPINE
- Products Intro:Brand：Acccorporation | OriginalID：API0003796 | Purity：95.00%
- Company Type: Trader
- Country/Region: UNITED STATES