Pimecrolimus
Pimecrolimus
- CAS:
- 137071-32-0
- MF:
- C43H68ClNO11
- MW:
- 810.45
Suppliers by country/region
Company Type
Properties
- Melting point:
- 135-136 °C
- Boiling point:
- 866.1±75.0 °C(Predicted)
- Density
- 1.19
- storage temp.
- Keep in dark place,Sealed in dry,2-8°C
- solubility
- DMSO (Slightly, Sonicated), Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.97±0.70(Predicted)
- color
- White to Off-White
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H332-H312-H302
- Precautionary statements
- P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
Use
Pimecrolimus is a semi-synthetic, macrocyclic lactone derived from ascomycin by activation of the 32-hydroxy group with a triflate ester, and nucleophilic substitution with chloride under phase transfer conditions to provide the chloro analogue. Pimecrolimus has been targeted for treatment of inflammatory skin disorders. Like all tacrolimus analogues, pimecrolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins.
22 India supplier list of "Pimecrolimus"
- Product Name:PIMECROLIMUS
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Pimecrolimus
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Pimecrolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Pimecrolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: AndhraPradesh,INDIA
- Product Name:Pimecrolimus
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Pimecrolimus
- Products Intro:Brand:sigma aldrich | Product Number:SML1437 | Purity:≥97%(HPLC)
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Pimecrolimus
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Pimecrolimus
- Company Type: Reagent
- Country/Region: Maharashtra,INDIA
- Product Name:PIMECROLIMUS
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:Pimecrolimus
- Company Type: Reagent
- Country/Region: Ahmedabad,INDIA