PP3
PP3
- CAS:
- 5334-30-5
- MF:
- C11H9N5
- MW:
- 211.22
Suppliers by country/region
Company Type
Properties
- Melting point:
- 214-217 °C
- storage temp.
- -20°C
- solubility
- DMF, DMSO, Hot methanol
- form
- Off-white solid
- color
- Whit to Off-White
- λmax
- 240nm(H2O (pH 1))(lit.)
- BRN
- 198460
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
- Hazard Codes
- Xn,Xi
- Risk Statements
- 36/37/38-22
- Safety Statements
- 36/37/39-26
- Hazard Note
- Irritant
- HS Code
- 29335995
Use
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. Several small molecule inhibitors of this signaling pathway have been developed as a therapeuptic strategy to abate abnormal Src kinase activity. PP3 is an inactive analog of the Src tyrosine kinase inhibitors PP1 and PP2 . At concentrations as high as 10 μM, it does not prevent proliferation mediated by a stem cell factor/mast cell growth factor in hematopoietic and cancer cell lines.[Cayman Chemical]
3 India supplier list of "PP3"
- Product Name:PP3
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:PP3
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
- Products Intro:Brand:tcichemicals | Product Number:A2737
- Company Type: Reagent
- Country/Region: New Delhi,INDIA
- Product Name:Amino-D
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA
- Product Name:1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
- Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
- Product Name:PP3
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:PP3
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Gamma-butyrolactone
- Product Name:4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine
- Products Intro:Purity: 95% | Package: $33.9/250mg;$103.9/1g;$465.9/5g;$2096.9/25g;Bulk package | CustNote: 95%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Chemicals and BioChemicals,Materials Science,ligands acting on targets,Proteins,Antibodies
- Product Name:PP3
- Company Type: Trader
- Country/Region: GERMANY