Procainamide hydrochloride
Procainamide hydrochloride
- CAS:
- 614-39-1
- MF:
- C13H22ClN3O
- MW:
- 271.79
Suppliers by country/region
Company Type
Properties
- Melting point:
- 165-168 °C
- Density
- 1.2027 (rough estimate)
- refractive index
- 1.6330 (estimate)
- storage temp.
- 2-8°C
- solubility
- H2O: soluble1g/10 mL, clear, greenish-yellow
- form
- Powder
- color
- White to slightly yellow
- Water Solubility
- soluble
- Sensitive
- Light Sensitive/Air Sensitive
- Merck
- 13,7845
- BRN
- 3729517
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36-37/39
- WGK Germany
- 3
- RTECS
- CV2295000
- HS Code
- 29242990
Use
Procainamide hydrochloride is metabolized through theaction of N-acetyltransferase. The product of enzymaticmetabolism of procainamide hydrochloride is N-acetylprocainamide(NAPA), which possesses only 25% of the activityof the parent compound.26 A study of the disposition ofprocainamide hydrochloride showed that 50% of the drugwas excreted unchanged in the urine, with 7% to 24% recoveredas NAPA.28,29 Unlike quinidine, procainamide hydrochlorideis bound only minimally to plasma proteins.Between 75% and 95% of the drug is absorbed from the gastrointestinaltract. Plasma levels appear 20 to 30 minutesafter administration and peak in about 1 hour.30Procainamide hydrochloride appears to have all of theelectrophysiological effects of quinidine. It diminishesautomaticity, decreases conduction velocity, and increasesaction potential duration and, thereby, the refractory periodof myocardial tissue. Clinicians have favored the use of procainamidehydrochloride for ventricular tachycardias andquinidine for atrial arrhythmias, even though the two drugsare effective in either type of disorder.
6 India supplier list of "Procainamide hydrochloride"
- Product Name:Procainamide hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Procainamide hydrochloride
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Procainamidehydrochloride
- Products Intro:Brand:sigma aldrich | Product Number:PHR1252 | Purity:PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Procainamide HCl 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.131378
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:4-Amino-N-[2-(diethylamino)ethyl]benzamidehydrochloride
- Products Intro:Brand:clearsynth | Product Number:CS-M-15739
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Procainamide hydrochloride
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:ProcainamideHydrochloride
- Products Intro:Brand:synzeal | Product Number:797054367
- Company Type: Trader
- Country/Region: Gujarat,INDIA
- Product Name:Procainamide hydrochloride
- Company Type: Reagent
- Country/Region: Haryana,INDIA
- Product Name:PROCAINAMIDE HYDROCHLORIDE
- Company Type: Manufacturer
- Country/Region: New Delhi,INDIA
- Product Name:ProcainamideHydrochloride
- Products Intro:Brand:pharmaffiliates | Product Number:PA1650000
- Company Type: Trader
- Country/Region: Haryana,INDIA