Riluzole
Riluzole
- CAS:
- 1744-22-5
- MF:
- C8H5F3N2OS
- MW:
- 234.2
Suppliers by country/region
Company Type
Properties
- Melting point:
- 116-118°C
- Boiling point:
- 296.3±50.0 °C(Predicted)
- Density
- 1.572±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥25 mg/mL
- form
- solid
- pka
- 2.96±0.10(Predicted)
- color
- white
- Merck
- 14,8223
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
- InChIKey
- FTALBRSUTCGOEG-UHFFFAOYSA-N
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H300
- Precautionary statements
- P301+P310+P330
- Hazard Codes
- T,Xi
- Risk Statements
- 25
- Safety Statements
- 45
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- RTECS
- DL2830000
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29342000
- Toxicity
- LD50 in mice (mg/kg): 46 i.p.; 67 orally (Mizoule)
Use
Riluzole belongs to the derivative of benzothiazole with neuroprotective, potential anti-depressant and anxiolytic activities, which is used in the treatment of a certain type of nerve disease called amyotrophic lateral sclerosis (ALS, also known as Lou Gehrigs disease). It is effective to delay the onset of ventilator-dependence or tracheostomy in selected patients, slow down the deterioration of this disease and probably prolong survival by approximately two to three months. Besides, studies have proved that riluzole has anti-depressant activity for refractory depression and serves as an anxiolytic in the treatment of obsessive-compulsive disorder and generalized anxiety disorder. However, riluzole does not cure the ALS and reverse nerve damage or muscle weakness. It is believed to function as an inhibitor of a natural substance called glutamate. It helps protect the nerves in the brain and spinal cord from too much of glutamate which may contribute to the nerve damage. Riluzole is available in both tablet and liquid form. The liquid formulation may be more suitable for patients with swallowing difficulties.
16 India supplier list of "Riluzole"
- Product Name:2-Amino-6-(trifluoromethoxy)benzothiazole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Maharashtra,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1MT
- Company Type: Manufacturer
- Country/Region: Karnataka,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: Telangana,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: Karnataka,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Reagent
- Country/Region: Tamil Nadu,INDIA
- Product Name:Riluzole
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Riluzole
- Products Intro:Brand:sigma aldrich | Product Number:R116 | Purity:solid
- Company Type: Trader
- Country/Region: Bangalore,INDIA