RN486
RN486
- CAS:
- 1242156-23-5
- MF:
- C35H35FN6O3
- MW:
- 606.69
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 868.6±65.0 °C(Predicted)
- Density
- 1.378±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥30.35 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
- form
- solid
- pka
- 13.95±0.10(Predicted)
- color
- Off-white to light yellow
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Use
RN486 displays similar functional activities in rodent models, effectively preventing type I and type III hypersensitivity responses. More importantly, RN486 produces robust anti-inflammatory and bone-protective effects in mouse CIA and rat adjuvant-induced arthritis (AIA) models. In the AIA model, RN486 inhibits both joint and systemic inflammation either alone or in combination with methotrexate, reducing both paw swelling and inflammatory markers in the blood.
1 India supplier list of "RN486"
- Product Name:Rn486 95%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.195162
- Company Type: Trader
- Country/Region: INDIA
- Product Name:RN486
- Products Intro:Purity: 98% HPLC | Package: 5G;10G;25G;50G;100G;250G;1KG
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:RN486
- Products Intro:Purity: 95%~99% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1KG
- Product Name:RN486
- Products Intro:Purity: 99.38% | Package: 1 mg；1 mL * 10mM (in DMSO)；10 mg；2 mg；25 mg；5 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:RN486
- Products Intro:Purity: 99% | Package: 5KG;1KG | CustNote: RN486
- Company Type: Trader
- Country/Region: CHINA
- Product Name:RN486
- Products Intro:Purity: 98% | Package: $153.9/5mg;$426.9/25mg;$652.9/50mg;$1175.9/100mg;Bulk package | CustNote: 98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:RN486
- Products Intro:Purity: 0.97 | Package: mgs,gs,kgs | CustNote: A890566
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:RN486
- Products Intro:Purity: 99% | Package: 1kg;10kg;100kg
- Company Type: Trader
- Country/Region: CHINA
-
5 mg$190.00
- Product Name:RN-486
- Products Intro:Brand：Caymanchem | Product Number：20536 | Purity：≥98%
- Company Type: Trader
- Country/Region: UNITED STATES
-
100 mg$800.001 g$2500.00
- Product Name:RN486
- Products Intro:Brand：dcchemicals | Product Number：DC5146 | Purity：>98%
- Company Type: Trader
- Country/Region: UNITED STATES