Salbutamol manufacturers and suppliers in india

Salbutamol

CAS:: 34391-04-3

MF:: C13H21NO3

MW:: 239.31

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Properties

Boiling point:: 433.5±40.0 °C(Predicted)

Density: 1.152±0.06 g/cm3(Predicted)

pka: 9.99±0.31(Predicted)

InChI: InChI=1/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3/t12-/s3

InChIKey: NDAUXUAQIAJITI-PLAQIDKDNA-N

SMILES: C1(=CC=C(O)C(CO)=C1)[C@@H](O)CNC(C)(C)C |&1:9,r|

Safety Information

Hazard Codes: Xn

Risk Statements: 22

Safety Statements: 36

Use

Salbutamol is a bronchodilator medication that eases muscle tension in the airways adjoining with the lungs and enhances the flow of air circulating through the lungs. It is a short-acting medication that is used in the treatment of acute bronchopulmonary disorders which may include chronic obstructive pulmonary disorders (COPD), and chronic instances of bronchospasm resultant of acute bronchitis and bronchial asthma. It can also be used for the prophylactic treatment of training-induced bronchospasm. Salbutamol indicates 29 times more selectivity for beta2 receptors as compared to beta1 receptors, which gives it a higher specificity for adrenergic receptors positioned in the heart. Salbutamol comprises a racemic combination of Sand Risomers, where the R-isomer illustrates a higher affinity (about 150 times more) than the S-isomer, which is directly linked to increased toxicity. This has also influenced the development of levalbuterol.