Semagacestat
Semagacestat
- CAS:
- 425386-60-3
- MF:
- C19H27N3O4
- MW:
- 361.44
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Properties
- Melting point:
- 208-212 °C
- Boiling point:
- 681.9±55.0 °C(Predicted)
- Density
- 1.22
- Flash point:
- 366.2℃
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 12.97±0.20(Predicted)
- color
- White
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
- HS Code
- 29337900
Use
Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis o f Alzheimer's disease (AD).
1 India supplier list of "Semagacestat"
- Product Name:Semagacestat;LY450139
- Products Intro:Package: 1 mL * 10mM (in DMSO);10 mg;100 mg;2 mg;25 mg;5 mg;50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Reagent
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits