Sevoflurane manufacturers and suppliers in india

Sevoflurane

Properties

Melting point:: <25 °C

Boiling point:: 58°C

Density: 1.505

Flash point:: 58°C

storage temp.: Refrigerator

solubility: Slightly soluble in water, miscible with ethanol (96 per cent).

Specific Gravity: 1.505

color: Colourless

Water Solubility: Slightly miscible with water.

Merck: 14,8475

BRN: 2041023

InChIKey: DFEYYRMXOJXZRJ-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319

Precautionary statements: P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313

Hazard Codes: Xi

Risk Statements: 36/37/38-36/38

Safety Statements: 26-36/37/39-36/37-23

RIDADR: UN 3334

WGK Germany: 3

RTECS: KO0737000

Hazard Note: Irritant

HS Code: 29091990

Use

Sevoflurane is a volatile, nonpungent, nonflammable, andnonexplosive liquid with a boiling point of 58.6°C. Theblood:gas partition coefficient is 0.65, the oil:gas partitioncoefficient is 50, and the MAC is 2.1%. Sevoflurane reactswith desiccated carbon dioxide adsorbents, to produce compounds(A and B) with known toxicity . The typeof CO2 absorbent used, the temperature of the absorbent,and the duration of exposure can influence the degree towhich sevoflurane breaks down. The major breakdownproduct, compound A, pentafluoroisopropenyl fluoromethylether, (PIFE, C4H2F6O) has been studied extensively.Compound A is nephrotoxic in rats and nonhuman primatesand remains a theoretical risk to humans. As discussedpreviously under the stability of inhaled anesthetics,sevoflurane breakdown by CO2 absorbents generates heatand has resulted in sporadic operating room fires.