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Sufentanil

Sufentanil

CAS:
56030-54-7
MF:
C22H30N2O2S
MW:
386.55

Properties

Melting point:
103-104℃
Boiling point:
493.1±40.0 °C(Predicted)
Density 
1.20 g/cm3
Flash point:
9℃
storage temp. 
2-8°C
solubility 
Practically insoluble in water, freely soluble in ethanol (96 per cent) and in methanol.
form 
A neat solid
pka
7.89±0.20(Predicted)
Water Solubility 
76mg/L(25 ºC)

Safety Information

Symbol(GHS) 

GHS02,GHS06,GHS08
Signal word 
Danger
Hazard statements 
H225-H301+H311+H331-H370
Precautionary statements 
P210-P260-P280-P301+P310-P311
Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
Toxicity
LD50 i.v. in mice: 18.7 mg/kg (Van Bever)

Use

Sufentanil is a narcotic analgesic with a greater potency and therapeutic ratio than its structural relative fentanyl. It appears to produce fewer cardiac effects and less respiratory depression than fentanyl, and thus is especially useful as an analgesic/anesthetic in open heart surgery.

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