Terfenadine
Terfenadine
- CAS:
- 50679-08-8
- MF:
- C32H41NO2
- MW:
- 471.67
Suppliers by country/region
Company Type
Properties
- Melting point:
- 145-152 °C
- Boiling point:
- 572.76°C (rough estimate)
- Density
- 1.0488 (rough estimate)
- refractive index
- 1.6310 (estimate)
- storage temp.
- 2-8°C
- solubility
- chloroform: soluble250 mg plus 5 ml of solvent, clear to very slightly hazy, colorless to faintly yellow
- pka
- pKa 9.21(H2O t = 25 I = 0.025) (Uncertain)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 0.001 g/100 mL (30 ºC)
Safety Information
- Symbol(GHS)
GHS07,GHS08,GHS09
- Signal word
- Danger
- Hazard statements
- H413
- Precautionary statements
- P273-P501
- Safety Statements
- 24/25
- WGK Germany
- 2
- RTECS
- TM4969000
- HS Code
- 29333999
- Toxicity
- LD50 orally in mice: >2000 mg/kg (Carr, Meyer)
Use
The first clinically interesting histamine H-receptor1 antagonists were introduced in the late 1940s and early 1950s. Several H-antihistaminics have a similar cardiac effect to that seen with astemizole1 and terfenadine. Serious cardiovascular adverse reactions have been reported when used concomitantly with imidazole antifungals and macrolide antibiotics. See also under astemizole.
3 India supplier list of "Terfenadine"
- Product Name:Terfenadine
- Products Intro:Brand:sigma aldrich | Product Number:T9652
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:Terfenadine 98%
- Products Intro:Brand：Glrinnovations | OriginalID：GLR19.013545
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Terfenadine
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Terfenadine
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:TerfenadineD6
- Products Intro:Brand:clearsynth | Product Number:CS-O-13202
- Company Type: Trader
- Country/Region: Hyderabad,INDIA
- Product Name:Terfenadine
- Products Intro:Brand:pharmaffiliates | Product Number:PA2014000
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Terfenadine (Fandachem)
- Products Intro:Purity: As coa | Package: As request | CustNote: 50679-08-8
- Company Type: Trader
- Country/Region: CHINA
- Product Name:terfenadine
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
- Products Intro:Purity: >=98% | Package: 1KG;9.8USD
- Company Type: Trader
- Country/Region: CHINA
$9.80/ 1KG
- Product Name:Terfenadine；MDL-991;(±)-Terfenadine
- Products Intro:Purity: 99.75% | Package: 1 mL * 10mM (in DMSO)；100 mg；200 mg；25 mg；50 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits