THIOLUTIN
THIOLUTIN
- CAS:
- 87-11-6
- MF:
- C8H8N2O2S2
- MW:
- 228.29
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Properties
- Melting point:
- 273-276℃
- Boiling point:
- 200°C (rough estimate)
- Density
- 1.4614 (rough estimate)
- refractive index
- 1.5690 (estimate)
- storage temp.
- −20°C
- solubility
- DMSO: 5 mg/mL
- form
- Yellow crystalline solid.
- pka
- 10.54±0.20(Predicted)
- color
- Brilliant-yellow needles from 1-butanol
- Stability:
- Stable for 3 years as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H300
- Precautionary statements
- P264-P270-P301+P310-P405-P501
- Hazard Codes
- T+,T
- Risk Statements
- 28
- Safety Statements
- 45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- JP1355000
- HS Code
- 29419090
- Toxicity
- LD50 in mice (mg/kg): 25 s.c.; 25 orally (Seneca)
Use
Thiolutin is an antibiotic first described by Tanner and co-workers in 1950. Resurgent interest in this class of microbial metabolites was stimulated by the discovery of their selective antitumor activity. Thiolutin is a potent inhibitor of bacterial and yeast RNA polymerases, and also inhibits mannan and glucan formation in fungi. Thiolutin suppresses tumor cell-induced angiogenesis in vivo.
0 India supplier list of "THIOLUTIN"
- Product Name:Thiolutin
- Products Intro:Brand:sigma aldrich | Product Number:T3450 | Purity:fromStreptomycesluteosporeus,≥95%(HPLC)
- Company Type: Trader
- Country/Region: INDIA
$1.00/ 1KG
- Product Name:THIOLUTIN
- Products Intro:Purity: 99.0% | Package: 1KG;1USD
- Company Type: Trader
- Country/Region: CHINA