Trimetazidine
Trimetazidine
- CAS:
- 5011-34-7
- MF:
- C14H22N2O3
- MW:
- 266.34
Suppliers by country/region
Company Type
Properties
- Boiling point:
- bp2 200-205°
- Density
- 1.092±0.06 g/cm3(Predicted)
- vapor pressure
- 0.003Pa at 25℃
- storage temp.
- Hygroscopic, Refrigerator, Under inert atmosphere
- solubility
- Chlorofrom (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.07±0.10(Predicted)
- color
- Colourless to Pale Yellow Gel
- Stability:
- Hygroscopic
- LogP
- 1.143 at 25℃ and pH6
Safety Information
- Symbol(GHS)
GHS02,GHS07,GHS05
- Signal word
- Danger
- Hazard statements
- H226-H314-H412-H302
- Precautionary statements
- P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P264-P270-P301+P312-P330-P501-P273-P501
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
Use
Trimetazidine (TMZ) is a piperazine derivative. Its trade name is Vasorel. Its chemical name is 1(2, 3, 4trimethoxy benzyl) piperazine dihydrochloride. It is an anti angina drug. It has the effect of antagonizing adrenaline, norepinephrine and vasopressin. It can relax vascular smooth muscle directly, reduce vascular resistance, increase blood flow of coronary and peripheral circulation, promote myocardial metabolism and production of myocardial energy. At the same time, it can reduce the oxygen consumption of the myocardium, thereby improving the balance between supply and demand of heart muscle oxygen. It can increase the tolerance to cardiac glycosides, increase the tolerance to exercise test in patients with angina pectoris, reduce the frequency of angina pectoris, and reduce the dosage of nitroglycerin. It is used in the treatment of coronary insufficiency, angina pectoris and old myocardial infarction. It can be used in combination with digitalis in patients with severe heart failure.
10 India supplier list of "Trimetazidine"
- Product Name:TRIMETAZIDINE HYDROCHLORIDE IH
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Himachal Pradesh,INDIA
- Product Name:Trimetazidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Trimetazidine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Gujarat,INDIA
- Product Name:Trimetazidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: Telangana,INDIA
- Product Name:Trimetazidine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: Gujarat,INDIA
- Product Name:Trimetazidine
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Trimetazidine
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:1-(2,3,4-Trimethoxybenzyl)piperazine
- Products Intro:Brand:pharmaffiliates | Product Number:PAI20001080
- Company Type: Trader
- Country/Region: Haryana,INDIA
- Product Name:Trimetazidine HCl
- Company Type: Reagent
- Country/Region: Mumbai,INDIA
- Product Name:Trimetazidine
- Company Type: Reagent
- Country/Region: Hyderabad,INDIA