WORTMANNIN
WORTMANNIN
- CAS:
- 19545-26-7
- MF:
- C23H24O8
- MW:
- 428.43
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Properties
- Melting point:
- 234-240 °C
- alpha
- +80.0~+105.0゜(20℃/D)(c=0.1,C2H5OH)
- Boiling point:
- 463.31°C (rough estimate)
- Density
- 1.2454 (rough estimate)
- refractive index
- 1.4480 (estimate)
- Flash point:
- 2℃
- storage temp.
- -20°C
- solubility
- DMSO: soluble
- form
- powder
- color
- off-white
- Sensitive
- Light Sensitive
- λmax
- 296nm(lit.)
- Merck
- 14,10053
- BRN
- 67676
- Stability:
- Stable for 1 year from date of purchase as supplied. Dried aliquots evaporated from ethanol may be stored at -20° for several months. Solutions however are not stable and must be used within one working day. Note
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H300+H310+H330
- Precautionary statements
- P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310
- Hazard Codes
- T+,T,Xi,Xn,F
- Risk Statements
- 26/27/28-36/37/38-36-20/21/22-11
- Safety Statements
- 28-36/37-45-37/39-26-16
- RIDADR
- UN 3462 6.1/PG 1
- WGK Germany
- 3
- RTECS
- CB9641000
- F
- 3-8-10
- HazardClass
- 6.1
- PackingGroup
- I
- HS Code
- 29322090
Use
Wortmannin is a steroidal metabolite belonging to the viridin group, isolated from Penicillium wortmannii in 1957. The structure was finally solved in 1968. Wortmannin exhibits broad spectrum antifungal activity, together with antitumor and antiinflammatory activity. Wortmannin is a potent inhibitor of phosphoinositide 3-kinase and myosin light chain kinase. Wortmannin also activates neutrophil and formyl-Met-Leu-Phe-mediated phospholipase D, inhibits autophagy, potentiates LPS-induced NO production and induces Alzheimer-like hyperphosphorylation in tau in vivo.
0 India supplier list of "WORTMANNIN"
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- Product Name:Wortmannin-CAS19545-26-7-Calbiochem
- Products Intro:Brand:sigma aldrich | Product Number:681675 | Purity:Wortmannin,CAS19545-26-7,isacell-permeable,potent,selective,andirreversibleinhib
- Company Type: Trader
- Country/Region: Bangalore,INDIA
- Product Name:WORTMANNIN
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$2.00/ 1kg