Zidovudine
Zidovudine
- CAS:
- 30516-87-1
- MF:
- C10H13N5O5
- MW:
- 283.24
Suppliers by country/region
Company Type
Properties
- Melting point:
- 113-115 °C (lit.)
- Boiling point:
- 410.43°C (rough estimate)
- alpha
- D25 +99° (c = 0.5 in water)
- Density
- 1.3382 (rough estimate)
- refractive index
- 47 ° (C=1, H2O)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- H2O: 50 mg/mL
- pka
- pKa 9.53(H2O t = 25.0±0.1 I = 0.00) (Uncertain)
- form
- Powder
- color
- White to Off-white
- Water Solubility
- 1-5 g/100 mL at 17 ºC
- Sensitive
- Light Sensitive & Hygroscopic
- Merck
- 14,10123
- BRN
- 3595791
- BCS Class
- 1,3
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChIKey
- HBOMLICNUCNMMY-BWZBUEFSSA-N
Safety Information
- Symbol(GHS)
GHS02,GHS06,GHS08
- Signal word
- Danger
- Hazard statements
- H303-H225-H301+H311+H331-H370-H351
- Precautionary statements
- P210-P260-P280-P301+P310-P311-P281-P501a-P201-P202-P308+P313-P405-P501
- Hazard Codes
- Xn
- Risk Statements
- 40-36/37/38-20/21/22
- Safety Statements
- 36/37/39-45-36-26
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 3
- RTECS
- XP2072000
- F
- 10
- Hazard Note
- Harmful
- HS Code
- 29349990
- Toxicity
- LD50 in male, female mice, male, female rats (mg/kg): 3568, 3062, 3084, 3683 orally; >750 i.v. (all species) (Ayers)
Use
Zidovudine, also known as azidothymidine (AZT), is an antiviral agent acting via reverse transcnptase inhibition. It was first launched in the U.K. and subsequently introduced in over a dozen countries for the management of severe manifestations of HIV infection. In patients with AIDS and ARC, zidovudine reduces the risk of opportunistic infections and prolongs survival time. In symptom-free patients it shows promise in halting further immunological deterioration.
27 India supplier list of "Zidovudine"
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg And 1MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Zidovudine
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Zidovudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA