Lamivudine
Lamivudine
- CAS:
- 134678-17-4
- MF:
- C8H11N3O3S
- MW:
- 229.26
Suppliers by country/region
- India(121)
- United States(69)
- CHINA(289)
- Canada(9)
- United Kingdom(21)
- Brazil(12)
- Europe(2)
- France(3)
- Germany(6)
- South Korea(7)
- Indonesia(1)
- Ukraine(1)
- Philippines(1)
- Russia(1)
- Colombia(1)
- Uruguay(1)
- Nigeria(1)
- Spain(1)
- Poland(1)
- Singapore(1)
- South Africa(1)
- Belgium(1)
- Malaysia(1)
- Nepal(1)
- United Arab Emirates(1)
- Mexico(1)
Company Type
Properties
- Melting point:
- 177 °C
- Boiling point:
- 475.4±55.0 °C(Predicted)
- alpha
- D21 -135° (c = 0.38 in methanol)
- Density
- 1.73±0.1 g/cm3(Predicted)
- refractive index
- -142 ° (C=1, MeOH)
- Flash point:
- 9℃
- storage temp.
- 2-8°C
- solubility
- water: soluble10mg/mL, clear
- pka
- 13.83±0.10(Predicted)
- form
- powder
- color
- white to beige
- Water Solubility
- 70g/L(temperature not stated)
- Merck
- 14,5352
- BCS Class
- 1,3
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
- InChIKey
- JTEGQNOMFQHVDC-NKWVEPMBSA-N
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Warning
- Hazard statements
- H361
- Precautionary statements
- P280
- Risk Statements
- 63-36/37/38
- Safety Statements
- 26-36
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 3
- RTECS
- UW7361333
- HS Code
- 29349990
Use
Lamivudine is the (–) enantiomer of a cytidine analogue with sulfur substituted for the 3'carbon atom in the furanose ring [(–) 2',3'-dideoxy, 3'-thiacytidine]. It has significant activity in vitro against both HIV-1 and HIV-2 as well as HBV. Lamivudine is phosphorylated to the triphosphate metabolite by cellular kinases. The triphosphate derivative is a competitive inhibitor of the viral reverse transcriptase.
121 India supplier list of "Lamivudine"
- Product Name:Lamivudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
- Company Type: Reagent
- Country/Region: INDIA
- Product Name:Lamivudine
- Products Intro:Purity: 95.87 | Package: Customize Packaging (As per customer requirement in Miligram)
- Company Type: Manufacturer
- Country/Region: INDIA
- Product Name:LAMIVUDINE
- Products Intro:Purity: 95-99% | Package: 1-5 gm, the rest upon order
- Company Type: Manufacturer
- Country/Region: INDIA