Гидрохлорид Хлорпромазин химические свойства, назначение, производство
Химические свойства
Crystalline Solid
Использование
Chlorpromazine hydrochloride is used in the treatment of schizophrenia; anti-emetic; as an antipsychotic in pills, injections, and suppositories; to relieve nausea and
vomiting associated with malignant diseases. In veterinary medicine, it is used as an anti-emetic, tranquilizer and sedative. It has slight
antihistaminic and anti adrenaline actions. It is a peripheral vasodilator and adepressant that blocks dopamine receptors in the central
nervous system.
Определение
ChEBI: The hydrochloride salt of chlorpromazine.
Общее описание
White or creamy-white odorless crystalline powder with very bitter taste. pH (5% aqueous solution) 4.0-5.5. pH (10% aqueous solution) 4-5.
Реакции воздуха и воды
Decomposes on exposure to air and light. becoming yellow, pink and, finally, violet. Water soluble.
Профиль реактивности
Chlorpromazine hydrochloride is incompatible in aqueous solution with sodium salts of barbiturates and other alkaline solutions. Solutions may be stabilized by addition of antioxidants and storing under nitrogen.
Пожароопасность
Flash point data for Chlorpromazine hydrochloride are not available; however, Chlorpromazine hydrochloride is probably combustible.
Профиль безопасности
Poison by ingestion,
intraperitoneal, intravenous, and
subcutaneous routes. An experimentalteratogen. Experimental reproductive
effects. An anti-emetic and antipsychotic
drug. Human systemic effects: anorexia
(human), excitement, gastrointestinal
changes, irritability, pulse rate increase,
respiratory stimulation, rigidity, somnolence,
sweating. Mutation data reported. When
heated to decomposition it emits very toxic
fumes of Cl-, NOx, and SOx.
Гидрохлорид Хлорпромазин препаратная продукция и сырье
сырьё
препарат