AZD 3759
AZD 3759
- CAS:
- 1626387-80-1
- MF:
- C22H23ClFN5O3
- MW:
- 459.9
Suppliers by country/region
Company Type
Properties
- Boiling point:
- 571.4±50.0 °C(Predicted)
- Density
- 1.358±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≥23 mg/mL in DMSO; insoluble in H2O; ≥8.32 mg/mL in EtOH with ultrasonic
- form
- solid
- pka
- 6.71±0.40(Predicted)
- color
- White to off-white
- InChIKey
- MXDSJQHFFDGFDK-CYBMUJFWSA-N
- SMILES
- N1(C(OC2C(OC)=CC3C(C=2)=C(NC2=CC=CC(Cl)=C2F)N=CN=3)=O)CCN(C)C[C@H]1C
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Use
AZD3759 is an EGFP inhibitor (Epidermal growth factor receptor tyrosine kinase inhibitor) with blood brain barrier (BBB) penetration. It has the potential for the treatment of non-small cell lung cancer (NSCLC), with brain metastases (BM) and leptomengingeal metastases (LM) since this type of cancer often contain a lot of activating mutations of the epidermal growth factor receptor (EGFR). It has excellent capability of penetrating the blood brain barrier to reach the central nervous system.
0 India supplier list of "AZD 3759"
- Product Name:AZD3759
- Products Intro:Brand:ajchemicals | Product Number:JDH-26450 | Purity:98+%
- Company Type: Trader
- Country/Region: New Delhi,INDIA
- Product Name:Zorifertinib
- Products Intro:Purity: 0.99 | Package: 1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Rocuronium bromide,Pancuronium bromide,Brigatinib,Zongertinib,Vecuronium bromide
- Product Name:AZD-3759
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:TIANFU CHEM---AZD 3759
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AZD3759
- Products Intro:Purity: As coa | Package: As request | CustNote: 1626387-80-1
- Company Type: Trader
- Country/Region: CHINA
- Product Name:AZD3759
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
- Product Name:AZD3759
- Products Intro:Purity: 98% | Package: 1g | CustNote: BOC Sciences also provides custom synthesis services for AZD3759.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:AZD 3759
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL