Cefroxadine
Cefroxadine
- CAS:
- 51762-05-1
- MF:
- C16H19N3O5S
- MW:
- 365.4
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Properties
- Melting point:
- 170° (dec)
- alpha
- D20 +87° (c = 1.093 in 0.1N HCl)
- Boiling point:
- 251°C (rough estimate)
- Density
- 1.3163 (rough estimate)
- refractive index
- 1.6390 (estimate)
- pka
- pKa 3.30±0.02(H2O t=35.0 I=0.00)(Approximate)
Safety Information
- Symbol(GHS)
GHS08
- Signal word
- Danger
- Hazard statements
- H334-H317
- Precautionary statements
- P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
- Toxicity
- LD50 in mice (mg/kg): >6000 orally; 7090 i.p. (Scartazzini, Bickel, 1978)
Use
Cefroxadine is closely related to cefradine, the structure differing only by the presence of a methoxy group replacing methyl at the C-3 position. The antimicrobial spectrum is identical to that of cefradine and cefalexin. A dose of 1 g as film-coated tablets produced mean peak plasma levels of 25 mg/L at 1 h. Absorption is depressed and delayed by administration with food. The plasma elimination half-life is 0.8 h, rising to 40 h in end-stage renal failure and falling to 3.4 h during hemodialysis. Around 85% of an oral dose is excreted unchanged in the urine. It is available in Japan.
0 India supplier list of "Cefroxadine"
- Product Name:Cefroxadine
- Products Intro:Purity: 99% | Package: 1kg;7USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$7.00/ 1kg
- Product Name:Cefroxadine
- Products Intro:Purity: 98% | Package: 100mg | CustNote: BOC Sciences also provides custom synthesis services for Cefroxadine.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Cefroxadine
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:cefroxadine
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
-
5mg$970.00
- Product Name:Cefroxadine
- Products Intro:Brand:TargetMol | Product Number:T21461 | Purity:98%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Cefroxadin
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Gamma-butyrolactone
- Product Name:Cefroxadine USP/EP/BP
- Products Intro:Purity: 99.9% | Package: 25kgs/Drum;200kgs/Drum | CustNote: FDA GMP CEP Approved Manufacturer
- Company Type: Trader
- Country/Region: CHINA
- Product Name:CEFROXADINE
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
- Product Name:CGP-9000
- Products Intro:Purity: 98% | CustNote: BOC Sciences also provides custom synthesis services for CGP-9000.
- Company Type: Reagent
- Country/Region: UNITED STATES
- Product Name:Cefroxadine
- Company Type: Trader
- Country/Region: CHINA