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Palbociclib
Palbociclib
- CAS:
- 571190-30-2
- MF:
- C24H29N7O2
- MW:
- 447.53
Properties
- Melting point:
- 200 ºC
- Boiling point:
- 711.5±70.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- storage temp.
- room temp
- solubility
- Soluble in DMSO (up to 2 mg/ml with warming)
- pka
- 8.66±0.10(Predicted)
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Safety Information
- Symbol(GHS)
GHS08,GHS09
- Signal word
- Warning
- Hazard statements
- H341-H361f-H373-H411
- Precautionary statements
- P201-P202-P260-P273-P280-P308+P313
Use
Palbociclib (Ibrane(R), Pfizer), a selective CDK4 and CDK6 inhibitor, received accelerated approval from FDA in 2015 for women with estrogen receptor-positive and HER2-negative breast cancer in combination with letrozole.
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